Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 10,600 | 5日内发货 | ||
50 mg | ¥ 13,800 | 5日内发货 | ||
100 mg | ¥ 17,500 | 5日内发货 |
Adapalene sodium salt 的其他形式现货产品:
产品描述 | Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist. |
靶点活性 | RARβ:2.3 nM (AC50), RARγ:9.3 nM (AC50), RARα:22 nM (AC50) |
体外活性 | Adapalene sodium salt is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Adapalene sodium salt is possibly more effective than tretinoin 0.025% gel in the treatment of acne vulgaris [1]. |
体内活性 | Thirty-six rats of either sex were divided into six groups (two control groups, and an etodolac, indomethacin, tretinoin, and adapalene sodium salt group) of six animals each. Each group was given different drugs or chemicals. The inhibitory activities of the drugs were determined on carrageenan-induced rat paw oedema. The inhibition rate (53.48%) in the tretinoin group was found to be higher than the adapalene sodium salt and controls (P < 0.05). Adapalene sodium salt was found to have an inhibition rate of 10.28%, and when compared with the other groups, it was found to have no statistically significant anti-inflammatory activity [2]. |
别名 | CD 271 sodium salt, 阿达帕林钠 |
分子量 | 435.519 |
分子式 | C28H28NaO3 |
CAS No. | 911110-93-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Adapalene sodium salt 911110-93-5 Others Adapalene sodium CD 271 sodium salt 阿达帕林钠 CD 271 sodium Inhibitor inhibitor inhibit